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Image of a woman in a lab coat pipetting into an eppendorf tube.

ActivMab
Discovery Solutions

Let us help you move faster from the bench to the clinic.

Our Technology

ActivMab   is a technology platform that leverages poxvirus biology and enables the discovery and development of antibodies against complex membrane proteins. 

Image of a poxvirus in blue and purple
Image of an antibody in blue, green and purple floating in a blue background
Image of a protein in blue spanning across a white bi-layer cell membrane with a large portion on the upper, extracellular side.

Our Services

Vaccinex offers our clients a complete antibody discovery service portfolio from antigen generation to antibody functional testing.

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With over 20 years of therapeutic antibody discovery experience, we are ready to work for you!

Image of a poxvirus in blue with GPCR proteins spanning the outer membrane in darker blue.

We can generate antigen virus for your protein of interest - all we need is the protein sequence.

Image of a mouse profile in silhoutte with a white antibody stencil on the body.

We immunize mice with our antigen virions and test for titer by flow cytometry. 

Image of a phagemid in teal with a white antibody stencil in the center.

Custom immunized phage libraries or our in-house human phage library available for selections.

Cartoon image of an antibody in teal.

Mammalian expression and affinity testing by ELISA or Flow Cytometry available.

Cartoon of an antibody binding to a GPCR that is spanning a bi-layer lipid membrane in blud.

CDR optimization and selection for improved affinity, functionality and development.

Cartoon of a 12 well plate with pink media in the wells.

Vaccinex has wide capabilities for functional testing of antibodies.

Cartoon of a white mouse with red eyes facing the viewer.

Vaccinex has extensive experience with various mouse models for disease.

Our ActivMab Business Alliance Team

Feel free to contact us at activmab@vaccinex.com or reach out to one of our Business Associates directly below.

Elaine Gersz, Research Scientist and BD Associate

egersz@vaccinex.com

Jessica Mayer, Research Scientist and BD Associate

jmayer@vaccinex.com

Ernest Smith photograph

Ernest Smith, Ph.D.

General Manager, ActivMab

Dr. Smith has been serving Vaccinex since 2001.  Prior to becoming General Manager, ActivMab, Ernest served as Vice President, Research and CSO. Dr. Smith received a B.A. in Biology from St. John Fisher College and an M.S. and a Ph.D. in Immunology from the Univeristy of Rochester.

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Email Dr. Smith at:

esmith@vaccinex.com

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