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Our Research

SEMA4D

Vaccinex’s lead clinical programs are focused on inhibition of semaphorin 4D (SEMA4D), a novel target and an important biological effector whose expression is implicated in the progression of a number of neurological diseases and cancers.

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SEMA4D & Neurology

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SEMA4D & Cancer

Drug Discovery

In addition to our lead antibody, pepinemab, Vaccinex has several preclinical antibodies in research and development.  These were discovered using our ActivMab antibody technology and have potential as future treatments for autoimmunity and cancer.

Vaccinex’s mission is to deliver innovative therapies that improve the lives of patients and provide treatment solutions for critical unmet needs. Through deep understanding of science and pathology of disease, we are pioneering a differentiated approach to treating neurologic diseases and cancer with novel antibody therapeutics. 

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Our scientists actively contribute to the scientific community through peer-reviewed publications, scientific posters, and presentations at leading industry and academic conferences.

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To see where we are presenting next, click here.

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